Abstract: This paper through the building inside and outside the enclosing wall of the various materials for economic, performance and other aspects of selection and research, to come up with suitable for substations inside and outside the wall of the material, in order to meet the construction of "resource-saving, environmentally friendly, industrialized," the requirements of the substation. It was found that AlumiManganese rock wool sandwich panel (LCF panel) is more suitable for substation exterior wall, which has a short construction period, good seismic performance, waterproof performance, good integrality, and strong applicability for such special project as substation, which is in line with the principle of whole life cycle construction. Light steel keel calcium silicate decorative panels are more suitable for substation walls, which makes the overall building sense of view has been improved, compared with the previous assembly enclosure wall material strength, fire, moisture and other properties have been greatly improved, and substation equipment installation and operation and maintenance is of great help.