Abstract: As the power grid expands and environmental complexities increase, traditional transmission line maintenance models are no longer sufficient to meet current needs. This paper proposes an intelligent operation and maintenance system for transmission lines based on multi-dimensional perception and integrated space-ground technologies. The system employs a combination of satellite remote sensing, drone inspection, intelligent security, and multi-sensor clusters to enable comprehensive real-time monitoring and hazard detection for transmission lines. Satellite remote sensing is utilized for macro-level monitoring of the transmission corridor environment, providing precise assessments of natural disaster risks and external damage threats. Drone inspection technology enables efficient multi-scenario applications, including infrared thermography and hazard detection of kite lines, significantly improving inspection efficiency. The intelligent security system, through multi-sensor coordinated perception, realizes three-dimensional spatial monitoring and smart alerts for the transmission line environment and equipment. The practical results demonstrate that this intelligent operation and maintenance system greatly enhances the safety, reliability, and inspection efficiency of transmission lines, driving innovation in transmission maintenance technologies.