Abstract: In order to realize the integrated intelligent error prevention and multi-discrimination of primary and secondary equipment, the substation sequence control and error prevention technology based on neural network is studied. The reasoning intelligent ticketing with intelligent anti-error verification is adopted, and the operation sequence of the primary and secondary equipment, as well as the status of the maintenance ticket and the operation ticket, etc., are checked hierarchically to realize integrated sequence control; integrated intelligent anti-virus The error optimization model adopts semantic analysis method and hidden Markov model to complete the word segmentation and part-of-speech tagging of the operation ticket content; after obtaining the action, object, status and other information of the operation ticket in combination with the grammar rules to extract the operation ticket content, the extraction result is input based on the In the improved neural network, the switch-off operation is corrected to realize the optimization of error prevention technology. The test results show that the completeness of the content extracted by this technology is above 0.90, and the content in the operation ticket is accurately obtained; it ensures the correctness of the action of the brake device, avoids the occurrence of malfunction and refusal, and realizes integrated intelligent error prevention, and Realize the cooperation and coordination of primary and secondary operations and multiple judgments.